07239
Fluka
γ-Aminobutyric acid
BioUltra, ≥99.0% (NT)
| Synonym: | 4-Aminobutanoic acid, GABA, Piperidic acid, Piperidinic acid |
| CAS Number: | 56-12-2 |
| Linear Formula: | NH2(CH2)3COOH |
| Molecular Weight: | 103.12 |
| Beilstein Registry Number: | 906818 |
| EC Number: | 200-258-6 |
| MDL number: | MFCD00008226 |
Description
| Biochem/physiol Actions | Major inhibitory neurotransmitter in brain; GABAA and GABAB receptor agonist; increases Cl− conductance. |
| Other Notes | Review - GABA: the road to neurotransmitter status1; Review: Activation and modulation of neuronal potassium channels by GABA2 |
Properties
| product line | BioUltra |
| assay | ≥99.0% (NT) |
| total impurities | insoluble matter, passes filter test |
| loss | ≤0.2% loss on drying |
| pH | 6.0-8.0 (25 °C, 1 M in H2O) |
| mp | 195 °C (dec.)(lit.) |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| anion traces | chloride (Cl-): ≤50 mg/kg |
| sulfate (SO42-): ≤50 mg/kg | |
| cation traces | Al: ≤5 mg/kg |
| As: ≤0.1 mg/kg | |
| Ba: ≤5 mg/kg | |
| Bi: ≤5 mg/kg | |
| Ca: ≤10 mg/kg | |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Li: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Mo: ≤5 mg/kg | |
| Na: ≤50 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Sr: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| λ | 1 M in H2O |
| UV absorption | λ: 260 nm Amax: 0.15 |
| λ: 280 nm Amax: 0.12 |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 2 |
| RTECS | ES6300000 |
References
| Cited Reference | 1. E. Roberts Recept. Biochem. Methodol. 5, 1, (1986) |
2. P.W. Gage Trends Neurosci. 15, 46, (1992) Abstract | |
| reference | Schwartz-Bloom, R.D., Sah, R. J. Neurochem. 77, 353, (2001) |
| Merck | Merck 13,429 |
| Beilstein | Beil. 4,IV,2600 |
| FT-IR 2 (1), 917:D / FT-IR 1 (1), 577:C / IR-Spectra (3), 345:C / IR-Spectra (2), 307:G / NMR-Reference 2 (1), 487:D / RegBook 1 (1), 659:A / Sax 6, 2236 / Sigma FT-IR 1 (1), 32:D / Structure Index 1, 97:B:6 |
